Renal proximal tubular epithelial cells: review of isolation
2020年11月10日 · In this review we will focus on human proximal tubular epithelial cells. We will cover human kidney culture models, cell sources, isolation, culture, immortalization, and characterization subdivided into morphological, phenotypical, and functional characterization.
Renal proximal tubular epithelial cells: review of isolation
2020年11月20日 · In this review we will focus on human proximal tubular epithelial cells. We will cover human kidney culture models, cell sources, isolation, culture, immortalization, and characterization subdivided into morphological, phenotypical, and functional characterization.
Renal tubular epithelial cells: the neglected mediator of ... - Nature
2018年11月13日 · In this review, we will focus on the role of TECs in tubulointerstitial fibrosis. We will follow the fate of a tubular cell and depict the intracellular changes after injury.
Renal Proximal Tubular Epithelial Cells: From Harvesting to Use …
2023年7月7日 · Currently, several protocols have been described for isolating desired kidney cells, of which the most isolated are the proximal tubular epithelial cells. These play a significant role in water homeostasis, acid-base control, reabsorption of compounds, and secretion of xenobiotics and endogenous metabolites.
Renal tubular epithelial cells response to injury in acute kidney ...
2024年9月1日 · The renal tubular epithelial cells (TECs) represent the central cell type affected by AKI, and their notable regenerative capacity is critical for the recovery of renal function in afflicted patients. The adaptive repair process initiated by surviving …
Cellular senescence of renal tubular epithelial cells in acute …
2024年2月5日 · Renal tubular epithelial cells (RTECs) stand as among the most critical cells in the renal parenchyma, significantly influencing the physiological functions of the kidneys. These...
Isolation and characterization of a primary proximal tubular epithelial ...
2013年6月14日 · Renal proximal tubular epithelial cells play a central role in renal physiology and are among the cell types most sensitive to ischemia and xenobiotic nephrotoxicity. In order to investigate the molecular and cellular mechanisms underlying the pathophysiology of kidney injuries, a stable and well-ch …
Generation and characterization of iPSC-derived renal proximal …
2021年6月2日 · Genome-wide RNA sequencing showed that PTL clustered within a kidney phenotype. PTL expressed proximal tubular-specific markers, including megalin (LRP2), showed a polarized phenotype, and were...
Primary Culture of Human Proximal Renal Tubular Epithelial Cells …
Establishing primary cultures of human proximal renal tubular epithelial cells (PTEC) provides a well-characterized in vitro model, phenotypically representative of PTEC in vivo.
Renal Proximal Tubular Cells: A New Site for Targeted Delivery …
Drug targeting to proximal renal tubular cells is an increasingly sophisticated technique with great potential for development. The proximal tubular cell is a very promising targeting cell because it can transport and accumulate carriers into proximal tubular cells via receptor-mediated endocytosis to achieve appropriate drug concentrations and ...
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