Poly(amidoamine) - Wikipedia
Poly (amidoamine), or PAMAM, is a class of dendrimer which is made of repetitively branched subunits of amide and amine functionality. PAMAM dendrimers, sometimes referred to by the trade name Starburst, have been extensively studied since their synthesis in 1985, [1] and represent the most well-characterized dendrimer family as well as the ...
聚乙二胺 - 百度百科
聚乙二胺是一种由乙二胺所合成高分子树枝状之聚合物,其形态为3D立体之团状物质,粒径约在1-20 nm。. 其最大的特色在於能够同时利用表面的NH2基与内部之孔隙来接合或包覆种类不同之物质,可应用於药物释放及生物的检测.依PAMAM dendrimer合成聚合物大小分为generation ...
Polyamidoamine (PAMAM) dendrimers synthesis, characterization …
2020年1月1日 · The study points out that dendrimers (PAMAM G 0) have a high adsorption capacity for nickel removal from aqueous solutions. Characterization of synthesized dendrimers were carried out by Scanning Electron Microscopy (SEM), Fourier Transform Infrared Spectroscopy (FTIR), UV-visible spectroscopy and zeta sizer analysis.
Polyamidoamine dendrimer-based materials for environmental …
2021年7月15日 · The continuous search for new and effective materials has led to the development of polyamidoamine (PAMAM) dendrimer-based materials for their use in wastewater treatment, precious metal recovery, sensing, and CO 2 capture. PAMAM with a three-dimensional branched architecture, accessible internal cavities, and easy surface functionalization are ...
PAMAM dendrimers as efficient drug and gene delivery …
Polyamidoamine (PAMAM) dendrimers are an example of a versatile and reproducible type of nanocarrier that can be loaded with drugs, and modified by attaching target-specific ligands that recognize receptors that are over-expressed on cancer cells.
(PDF) Poly(amidoamine) (PAMAM) Dendrimers: Synthesis and Biological ...
2020年5月20日 · PAMAM dendrimers have many outstanding characteristics that make them highly suited to biological applications, including their peptide-mimicking amide backbones, numerous...
Poly(amidoamine) (PAMAM) dendrimers: from biomimicry to …
2001年4月15日 · Poly(amidoamine) (PAMAM) dendrimers are the first complete dendrimer family to be synthesized, characterized and commercialized. Based on this extensive activity, they are recognized as a unique new class of synthetic nanostructures.
A polyamidoamine (PAMAM) derivative dendrimer with high …
2021年5月4日 · In this study, we developed a poly(amidoamine) (PAMAM) derivative dendrimer (denoted as fourth generation-N,N-diethylaminoethyl (G4-DEEA)) for efficient loading of Toll-like receptor 7 and 8 (TLR7/8) agonist (R848) to remodel the TIME for potent cancer immunotherapy.
New Advances in General Biomedical Applications of PAMAM Dendrimers
The PAMAM dendrimer core can be composed of linear chain molecules containing primary amines. The most commonly compounds are ethylenediamine (EDA, four core multiplicity, meaning, therefore, up to four branches), ammonia (three core multiplicity), or cystamine (four core multiplicity), as shown in Figure 2 [7].
Chemical characterization (LC–MS–ESI), cytotoxic activity and ...
2021年4月15日 · Generation 4 polyamidoamine dendrimers (G4-PAMAMs) have several biological applications as drug 4, peptide 5, and DNA carriers 6. It can also transfer genetic material agents into cells 7, among...