Linear epitope - Wikipedia
In immunology, a linear epitope (also sequential epitope) is an epitope—a binding site on an antigen—that is recognized by antibodies by its linear sequence of amino acids (i.e. primary …
Human neutralizing antibodies to cold linear epitopes and
2023年3月17日 · Antibody hr2.016 targets the stem helix and neutralizes SARS-CoV-2 variants. Antibody sd1.040 binds to subdomain 1, synergizes with antibody rbd.042 for neutralization, …
Dissecting Antibodies with Regards to Linear and Conformational ...
Here, we describe how epitope-specific fractionation of polyclonal sera based on epitope mapping and affinity capture on chromatography columns can be used to determine the ratio of …
An Introduction to Antibodies: Antigens, Epitopes and Antibodies
In a denatured protein, only the linear epitope may be recognized. Hence, in protocols where a denatured protein is used, such as in Western blotting, an antibody that recognizes a linear …
PAbFold: Linear Antibody Epitope Prediction using AlphaFold2
2024年4月19日 · We found that this AlphaFold2 pipeline, which we call PAbFold, was able to accurately flag known epitope sequences for several well-known antibody targets (HA / Myc) …
PAbFold: Linear Antibody Epitope Prediction using AlphaFold2
2024年4月19日 · In this project we test a method we call PAbFold, a LocalColabFold-based pipeline to identify epitopes for several well-known linear-epitope antibodies from sequence …
Human neutralizing antibodies to cold linear epitopes and
2023年1月26日 · Using coldspot-guided antibody discovery, a screening approach that focuses on portions of the virus spike glycoprotein that are both functionally relevant and averse to …
Dissecting Antibodies with Regards to Linear and Conformational …
2015年3月27日 · The aim of this study was to determine the proportions of antibodies towards linear and conformational epitopes elicited by immunizations with recombinant protein …
High-resolution Mapping of Linear Antibody Epitopes Using …
2012年12月1日 · Here, we present the first report on the feasibility of using ultrahigh-density peptide microarrays to address antibody specificities in casu mapping the fine specificity of …
Development of Detection Antibody Targeting the Linear Epitope …
2024年4月18日 · We clarified the epitope of the optimal linear peptide and prepared colloidal gold immunochromatographic strips with the antibody targeting this epitope, which demonstrated …
- 某些结果已被删除