Hyperchloremic Acidosis - StatPearls - NCBI Bookshelf
2023年5月8日 · Hyperchloremic metabolic acidosis is a pathological state that results from bicarbonate loss, rather than acid production or retention. Bicarbonate loss leading to hyperchloremic metabolic acidosis occurs in a variety of ways: gastrointestinal (GI) causes, renal causes, and exogenous causes.
Metabolic Acidosis - StatPearls - NCBI Bookshelf
2023年7月17日 · Metabolic acidosis is characterized by an increase in the hydrogen ion concentration in the systemic circulation resulting in a serum HCO3 less than 24 mEq/L. Metabolic acidosis is not a benign condition and signifies an underlying disorder that needs to be corrected to minimize morbidity and mortality.
Diagnosis of metabolic acid-base disorders & Anion-gap metabolic acidosis
2024年6月29日 · (a) Metabolic acidosis due to chronic respiratory alkalosis is extremely rare (unless a patient is being mismanaged on mechanical ventilation). This is a bit of a zebra. (b) Metabolic alkalosis due to chronic respiratory acidosis is common in patients with hypercapnia of any etiology (most commonly COPD, obesity hypoventilation syndrome, or ...
Hyperchloremic acidosis - Wikipedia
Hyperchloremic acidosis is a form of metabolic acidosis associated with a normal anion gap, a decrease in plasma bicarbonate concentration, and an increase in plasma chloride concentration [1] (see anion gap for a fuller explanation).
Both respiratory (e.g., CO2 tension) and metabolic factors (e.g., lactic acid) affect H+.3 Classically, decisions based on blood gas analysis are based on the apparent pH, in relation to the pCO2 (carbon dioxide tension), further assisted by the bicarbonate concentration (HCO3 -) and base excess variables, can assess whether derangements are lik...
Causes and effects of hyperchloremic acidosis - Critical Care
2006年6月29日 · Our large, observational study did reveal a trend showing hyperchloremic metabolic acidosis was worse than the no metabolic acidosis group; however, it did not reach statistical significance. Thus, we suspect that the effects of hyperchloremia, especially when modest, are unlikely to influence outcome for most patients.
Hyperchloremic Acidosis - PubMed
2023年5月8日 · Hyperchloremic acidosis is a disease state where acidosis (pH less than 7.35) develops with an increase in ionic chloride. Understanding the physiological pH buffering system is important. The major pH buffer system in the human body is the bicarbonate/carbon dioxide (HCO3/CO2) chemical equilibrium system.
A Quick Reference on Hyperchloremic Metabolic Acidosis
Hyperchloremic metabolic acidosis is the result of chloride retention, excessive loss of sodium relative to chloride, or excessive gain of chloride relative to sodium. Clinical signs are related to the underlying disease that accompanies the metabolic acidosis.
Hyperchloremic metabolic acidosis is the clinical combination of a non-respirato-ry acidosis, i.e., metabolic acidosis caused by an increase in the plasma concentration of chloride to supraphysiological levels. Currently, there are two explanations for the pathophysiology of hyperchloremic metabolic acidosis.
Hyperchloremic normal gap metabolic acidosis - PubMed
Metabolic acidosis can be of a kidney origin or an extrarenal cause. Assessment of urinary ammonium excretion by calculating the urine anion gap or osmolal gap is a useful method to distinguish between these two causes.