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c - Implementation of __builtin_clz - Stack Overflow
2012年2月19日 · CLZ (count leading zero) and BSR (bit-scan reverse) are related but different. CLZ equals (type bit width less one) - BSR. CTZ (count trailing zero), also know as FFS (find first set) is the same as BSF (bit-scan forward.)
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Pharmacokinetic and pharmacodynamic actions of clozapine-N …
Here we compare the pharmacokinetics, off-target effects and efficacy of CNO, clozapine (CLZ) and compound 21 (Cmpd-21) at the inhibitory DREADD human Gi-coupled M4 muscarinic receptor (hM4Di). The half maximal effective concentration (EC 50) of CLZ was substantially lower (0.42 nM) than CNO (8.1 nM); Cmpd-21 was intermediate (2.95 nM). CNO was ...
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Optimizing clozapine for chemogenetic neuromodulation of …
2020年4月7日 · Clozapine (CLZ) has been proposed as an agonist for Designer Receptors Exclusively Activated by Designer Drugs (DREADDs), to replace Clozapine-N-oxide (CNO); however, there are no reliable...
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Community-Based Service Use After Clozapine Treatment: A …
2023年4月5日 · To examine changes in utilization before and after clozapine treatment, we used a mirror-image design in which individuals served as their own control, facilitating a within-person comparison.
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Olanzapine Sensitization and Clozapine Tolerance: From ... - Nature
2012年11月7日 · In adult rats, repeated olanzapine (OLZ) treatment causes an enhanced disruption of avoidance response (sensitization), whereas repeated clozapine (CLZ) treatment causes a decreased disruption ...