Central Sensitisation - Physiopedia
Central sensitisation is characterized by the absence of peripheral sources of nociceptive input, therefore it seems more appropriate to use a treatment with a top-down mechanism, activating descending nociceptive processing together with decreasing descending nociceptive facilitation.
Central Sensitization: A Generator of Pain Hypersensitivity ...
Central sensitization is responsible for many of the temporal, spatial, and threshold changes in pain sensibility in acute and chronic clinical pain settings and exemplifies the fundamental contribution of the central nervous system to the generation of pain hypersensitivity.
Central sensitization, chronic pain, and other symptoms ...
2023年4月1日 · In central sensitization, the central nervous system undergoes structural, functional, and chemical changes that make it more sensitive to pain and other sensory stimuli. Central sensitization provides an explanatory framework for …
Central sensitisation in chronic pain conditions: latest ...
2021年3月30日 · Central sensitisation, defined as an amplification of neural signalling within the CNS that elicits pain hypersensitivity, has been investigated as a reason for this discrepancy.
Central sensitization: Implications for the diagnosis and ...
Central sensitization manifests as pain hypersensitivity, particularly dynamic tactile allodynia, secondary punctate or pressure hyperalgesia, aftersensations, and enhanced temporal summation.
Central Sensitization: Central Mechanisms of Neuroma and ...
2024年8月22日 · This chapter describes the anatomy and physiology of the nociceptive system, as well as the molecular mechanisms that underlie central sensitization. We also provide clinical examples of central sensitization as well as surgical approaches to …
The neurobiology of central sensitization - Harte - 2018 ...
Central sensitization refers to the amplification of pain by central nervous system mechanisms. Classically described as a consequence of ongoing nociceptive input, it is increasingly recognized that central sensitization also occurs independent of peripheral injury or inflammation.