Planarian - Wikipedia
Two-headed planaria regenerates can be induced by treating amputated fragments with pharmacological agents that alter levels of calcium, cyclic AMP, and protein kinase C activity in cells, [36] as well as by genetic expression blocks (interference RNA) to the canonical Wnt/β-Catenin signalling pathway.
Planarian regeneration in space: Persistent anatomical, behavioral, …
Remarkably, the head‐less middle fragment regenerated into a double‐headed phenotype (Fig. 5), demonstrating that the major body‐plan modification that occurred in this animal is stable and persists for at least two rounds of cutting and subsequent regeneration after exposure to space travel. Given the long‐term alterations observed in ...
Microgravity: Space worms with two heads | Nature Astronomy
2017年6月19日 · Planaria are flatworms that can regrow all of their body parts, even when cut into separate head, pharynx and tail segments, making them a popular model for regeneration studies. Now Junji...
Why Two Heads? - BioInteractive
2018年11月19日 · They can regenerate parts of their bodies using adult stem cells called neoblasts. When part of a planarian is cut off, its neoblasts multiply to make more stem cells. Some of these stem cells then differentiate into the cells needed to regrow the missing body parts.
Planarian, the Master of Regeneration - Rs' Science
The process of planarian’s whole-body regeneration. A fragment of planarian can regrow into a new animal in about two weeks. As you can see in the image below, a planarian cut into five pieces become five new planaria. The head piece regrows a body and a tail. The tail piece gains a new head and a body.
Worm Grows 2 Heads in Space, Surprising Scientists
2017年6月13日 · Planarian flatworms (Dugesia japonica) are very flat and tiny, measuring about 0.2 to 0.4 inches (0.5 to 1 centimeter) in length, study co-author Michael Levin, a professor of biology at Tufts...
Neural control of body-plan axis in regenerating planaria
2019年4月16日 · Our model also explains several outstanding puzzles in planarian regeneration, such as how self-assembling, self-scaling morphogen gradients can form in pieces of different size and location across the worm; the mechanistic origin of various heteromorphoses (e.g. one-headed, two-headed, missing-head or missing-tail outcomes) under a range of ...
Wnt/β-catenin signalling is required for pole-specific ... - Nature
2023年1月18日 · Inhibition of these genes produces a shift in the polarity, originating two-tailed or two-headed planarians after silencing notum or wnt1, respectively 22,23,24.
Two-Headed Space Worms - NPR
2017年8月24日 · What in the world are Planarian Flatworms? Why in the world did scientists send them on a mission to outer space? And where in the world are their mouths if not on their heads?! Join Guy Raz and...
Evolutionary dynamics of whole-body regeneration across planarian ...
2023年10月19日 · A comparative analysis of head-regeneration capacity across planarian species in a phylogenetic context reveals multiple Wnt-dependent transitions in head-regeneration ability and proposes...