Signet-ring cells in pleural and peritoneal effusions identified on ...
2022年3月4日 · Signet-ring cells (SRCs) in effusion specimens represent a diagnostic challenge. In this study, a consecutive series of pleural and peritoneal effusions with benign SRCs are examined and compared with malignant SRCs. We reviewed consecutive Wright-stained serous effusion slides and searched for cases with SRCs.
Signet-ring Cells in Pleural and Peritoneal Effusions Identified on ...
2014年9月1日 · The presence of signet-ring cells (SRCs) in serous effusion specimens poses a diagnostic challenge. Not only high grade adenocarcinomas may present as SRCs; histiocytes and reactive mesothelial cells can be a perfect mimic.
Signet-ring cells in pleural and peritoneal effusions identified on ...
2022年3月4日 · Objectives: Signet-ring cells (SRCs) in effusion specimens represent a diagnostic challenge. In this study, a consecutive series of pleural and peritoneal effusions with benign SRCs are examined and compared with malignant SRCs. Material and methods: We reviewed consecutive Wright-stained serous effusion slides and searched for cases with SRCs.
Cytologic diagnosis and differential diagnosis of histiocytic signet ...
2024年9月2日 · Our study provides a detailed characterization of benign histiocytic signet ring cells in effusion cytology. The differential diagnosis of histiocytic signet ring cells is broad. The most important differential diagnoses are metastatic adenocarcinoma and epithelioid signet ring cell mesothelioma.
A rare case of signet ring cell lymphoma: Diagnosis aided by ...
Pleural fluid cytology also showed typical signet ring cells in addition to lymphocytes and mesothelial cells. These signet ring cells showed negativity for the mesothelial marker HBME1on immunocytochemistry [Figure 1c]. The lymph node biopsy showed classical follicular lymphoma with some diffuse areas [Figure 1d]. The signet ring cells were ...
The panorama of different faces of mesothelial cells - PMC
All effusions in serous cavities represent a pathologic processes secondary to inflammatory, neoplastic, hemodynamic, or mechanical/traumatic etiologies. This elicits reactive changes in the extremely sensitive mesothelial cells lining the serosal surfaces.
Diagnostic mesothelioma biomarkers in effusion cytology
2021年1月19日 · Pleural biopsy is the gold standard for diagnosis, in which the identification of pleural invasion by atypical mesothelial cell is a major criterion. Pleural effusion is usually the first sign of disease; therefore, a cytological specimen is often the initial or …
Serous Fluid Cytopathology - SpringerLink
2014年1月1日 · The differential diagnosis of so-called “signet ring” cells in effusion cytology is broad, including both benign and malignant conditions. In benign reactive mesothelial cells, they can have “signet ring” cell features. Both metastatic adenocarcinomas of the lung and stomach can present “signet ring” cell morphology.
Significance of "signet-ring cells" seen in exfoliative and …
"Signet ring cell" (SRC) is a phenotypic designation for a cell with a large clear cytoplasmic vacuole displacing the nucleus to the periphery. Our study focuses on the cytopathologic significance of SRCs in the context of diagnostic range, ancillary studies, and clinical prognosis.
Pleural fluid cytologic examination shows tumor cells with Signet ring …
Signet ring cell carcinoma (SRCC) of the lung is a rare variant of pulmonary adenocarcinoma. Because the majority of SRCCs in the lung are metastatic tumors from stomach, colon, or breast....