Primidone - StatPearls - NCBI Bookshelf
2024年2月28日 · Primidone, an aromatic anticonvulsant, holds a pivotal role in the comprehensive management of complex, partial, and generalized seizures prevalent in individuals who have epilepsy. This program delves into crucial facets essential for adept clinical application: indications, contraindications, pharmacological activity, and adverse events ...
Antiseizure medications: Mechanism of action, pharmacology ... - UpToDate
2024年7月29日 · While sharing a common property of suppressing seizures, antiseizure medications have many different pharmacologic profiles that are relevant when selecting and prescribing these agents in patients with epilepsy and other conditions.
Primidone - Wikipedia
Primidone is an anticonvulsant of the barbiturate class; [7] however, its long-term effect in raising the seizure threshold is likely due to its active metabolite, phenobarbital. [10] The drug’s other active metabolite is phenylethylmalonamide (PEMA). Primidone was approved for medical use in the United States in 1954. [7]
Primidone: Uses, Interactions, Mechanism of Action - DrugBank …
Primidone is an anticonvulsant used to treat essential tremor as well as grand mal, psychomotor, and focal epileptic seizures. 15 Primidone was developed by J Yule Bogue and H C Carrington in 1949. 10
Primidone: Dosage, Mechanism/Onset of Action, Half-Life
2020年2月17日 · Includes Primidone indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. Skip to Content
Primidone - PubMed
2024年2月28日 · Primidone, an aromatic anticonvulsant, holds a pivotal role in the comprehensive management of complex, partial, and generalized seizures prevalent in individuals who have epilepsy. This program delves into crucial facets essential for adept clinical application: indications, contraindications, phar …
Primidone | C12H14N2O2 | CID 4909 - PubChem
Primidone is a pyrimidone that is dihydropyrimidine-4,6 (1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures. It has a role as an environmental contaminant, a xenobiotic and an anticonvulsant. View More... 5-ethyl-5-phenyl-1,3-diazinane-4,6-dione.
Primidone - an overview | ScienceDirect Topics
Primidone is a barbiturate anticonvulsant. It is metabolized into phenobarbital and phenylethylmalonamide (PEMA), but neither of its metabolites alone is efficacious in treating ET (Baumel et al., 1972). Primidone’s proposed mechanism of action in ET is through modulating the GABA receptors.
Primidone: Package Insert / Prescribing Info - Drugs.com
2024年11月4日 · Primidone tablets used alone or concomitantly with other anticonvulsants, are indicated in the control of grand mal, psychomotor, and focal epileptic seizures. It may control grand mal seizures refractory to other anticonvulsant therapy. Primidone is contraindicated in:
Mysoline (primidone) dosing, indications, interactions, adverse …
Medscape - Indication-specific dosing for Mysoline (primidone), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost...