NAD(P)H dehydrogenase (quinone 1) - Wikipedia
NAD(P)H dehydrogenase [quinone] 1 is an enzyme that in humans is encoded by the NQO1 gene. [5] This protein-coding gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a 2-electron reductase (enzyme).
NQO1 Gene - GeneCards | NQO1 Protein | NQO1 Antibody
2024年12月10日 · NQO1 (NAD(P)H Quinone Dehydrogenase 1) is a Protein Coding gene. Diseases associated with NQO1 include Tardive Dyskinesia and Colon Adenocarcinoma. Among its related pathways are Nuclear events mediated by NFE2L2 and Vitamin K metabolism and activation of dependent proteins.
NAD(P)H quinone oxidoreductase (NQO1): an enzyme which …
NAD (P)H quinone oxidoreductase 1 (NQO1) catalyses the two electron reduction of quinones and a wide range of other organic compounds. Its physiological role is believed to be partly the reduction of free radical load in cells and the detoxification of xenobiotics.
NQO1: A target for the treatment of cancer and neurological …
NAD (P)H quinone oxidoreductase 1 (NQO1) is a multi-functional protein that catalyses the reduction of quinones (and other molecules), thus playing roles in xenobiotic detoxification and redox balance, and also has roles in stabilising apoptosis regulators such as p53.
The diverse functionality of NQO1 and its roles in redox control
2021年5月1日 · Established roles for NQO1 include a superoxide reductase activity, NAD+ generation, interaction with proteins and their stabilization against proteasomal degradation, binding and regulation of mRNA translation and binding to …
The diverse functionality of NQO1 and its roles in redox control
Established roles for NQO1 include a superoxide reductase activity, NAD + generation, interaction with proteins and their stabilization against proteasomal degradation, binding and regulation of mRNA translation and binding to microtubules including the mitotic spindles.
Functions of NQO1 in Cellular Protection and CoQ
NQO1 is one of the two major quinone reductases in mammalian systems. It is highly inducible and plays multiple roles in cellular adaptation to stress. A prevalent polymorphic form of NQO1 results in an absence of NQO1 protein and activity so it is ...
NQO1 NAD(P)H quinone dehydrogenase 1 [ (human)] - National …
Gene ID: 1728, updated on 26-Nov-2024. This gene is a member of the NAD (P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones.
Review on NAD(P)H dehydrogenase quinone 1 (NQO1) pathway
This review outlines the NQO1 structure, mechanism of action to inhibit the cancer cell, functions of NQO1 against oxidative stress, drugs acting on NQO1 pathways, clinical significance.
Review NAD (P)H:quinone acceptor oxidoreductase 1 (NQO1), a ...
2010年9月1日 · NAD (P)H:quinone acceptor oxidoreductase 1 (NQO1) is a widely-distributed FAD-dependent flavoprotein that promotes obligatory 2-electron reductions of quinones, quinoneimines, nitroaromatics, and azo dyes, at rates that are comparable with NADH or NADPH.