Lipogenesis - Wikipedia
In biochemistry, lipogenesis is the conversion of fatty acids and glycerol into fats, or a metabolic process through which acetyl-CoA is converted to triglyceride for storage in fat. [1]
10.4: Lipid Metabolism - Biology LibreTexts
2022年7月30日 · This process, called lipogenesis, creates lipids (fat) from the acetyl CoA and takes place in the cytoplasm of adipocytes (fat cells) and hepatocytes (liver cells). When you eat more glucose or carbohydrates than your body needs, your system uses acetyl CoA to …
Physiological and pathological roles of lipogenesis - Nature
2023年5月4日 · Lipogenesis is a process that converts carbohydrates and other substrates into fatty acids, which are then stored as TAGs. Key enzymes involved in lipogenesis are exquisitely regulated by...
The Subtle Balance between Lipolysis and Lipogenesis: A Critical …
Lipolysis is a catabolic pathway that promotes mobilization of metabolic fuel from adipose to peripheral tissues in response to appropriate energy demands. Lipolysis occurs mainly in the adipose tissue. The major determinant of total FFA release is …
De novo lipogenesis in the liver in health and disease: more than …
Hepatic de novo lipogenesis (DNL) is a fundamental biosynthetic pathway within the liver, contributing to the lipids that are stored and secreted by hepatocytes (Jensen‐Urstad & Semenkovich, 2012).
De novo lipogenesis in health and disease - PubMed
Background: De novo lipogenesis (DNL) is a complex and highly regulated metabolic pathway. In normal conditions DNL converts excess carbohydrate into fatty acids that are then esterified to storage triacylglycerols (TGs). These TGs could later provide energy via β-oxidation.
Lipogenesis - an overview | ScienceDirect Topics
Lipogenesis is defined as the synthesis of fatty acids from nonlipid precursors. It is a pathway for metabolism of excess carbohydrate and is activated by high carbohydrate availability.
SREBP-regulated lipid metabolism: convergent physiology - Nature
2017年8月29日 · Sterol regulatory-element binding proteins (SREBPs) are transcription factors that regulate the expression of genes involved in lipid synthesis and function as key nodes of convergence...
Lipogenesis - an overview | ScienceDirect Topics
Lipogenesis is the synthesis of esterified fatty acids, which form triglycerides from carbohydrates or other energy sources acquired in the diet. Lipogenesis is regulated by the transcription factor sterol regulatory element-binding protein-1c (SREBP-1c).
Lipogenesis is a process that converts carbohydrates and other substrates into fatty acids, which are then stored as TAGs. Key enzymes involved in lipogenesis are exquisitely regulated by...