Laser capture microdissection - Wikipedia
Laser-capture microdissection (LCM) is a method to procure subpopulations of tissue cells under direct microscopic visualization. LCM technology can harvest the cells of interest directly or can isolate specific cells by cutting away unwanted cells to …
Laser capture microdissection: from its principle to applications …
History and the principle of laser capture microdissection (LCM): LCM, also known as laser microdissection and pressure catapulting, is one of the most powerful and useful techniques in various research areas where isolation of heterogeneous cell population is required.
Laser Capture Microdissection in the Tissue Biorepository
Laser capture microdissection (LCM) is a state-of-the-art technology for isolating pure cell populations from a heterogeneous tissue specimen. It can precisely target and capture the cells of interest for a wide range of downstream assays.
An Introduction to Laser Microdissection - Leica Microsystems
2024年10月9日 · Laser microdissection (LMD) is a selective process for preparing samples when performing protein, DNA, or RNA analysis. LMD is needed due to the heterogeneity of histological and biological specimens.
Laser-capture microdissection - Nature Protocols
2006年6月27日 · Laser-capture microdissection (LCM) is a method to procure subpopulations of tissue cells under direct microscopic visualization. LCM technology can harvest the cells of interest directly or...
Laser Capture Microdissection: Precision in Cellular Analysis
Laser capture microdissection (LCM) is a vital technique for isolating specific cells from tissue sections. It allows researchers to collect pure cell populations without contamination. This precision in capturing individual cells is crucial for accurate and detailed cellular analysis.
Laser Capture Microdissection in the Spatial Analysis of …
Laser capture microdissection (LCM) is a powerful technique used to isolate a targeted cell group with extreme microscopic precision. LCM presents itself as a solution to tackling the problem of tissue heterogeneity in molecular analysis.
Laser microdissection: sample preparation and applications
2020年11月4日 · Laser microdissection (LM) is a rapid, easy, one-step, and efficient method of conserving and isolating single cell or cell clusters from fixed tissue sections under direct microscopic visualization. LM is currently the only method that can be used to isolate homogeneous cells from heterogeneous tissue.
Laser Capture Microdissection: Methods and Applications
2011年1月1日 · Laser capture microdissection (LCM) offers a simple, one-step process that provides scientists with a fast and dependable method of preserving and isolating single cells, or clusters of cells, from tissue sections by direct microscopic visualization (2, 4, 5).
Laser Capture Microdissection - Thomas Jefferson University
Laser capture microdissection (LCM) is a technique that allows the precise procurement of enriched cell populations from a heterogeneous tissue under direct microscopic visualization.
Gentle Laser Microdissection for Precise Cell Isolation | ZEISS
Laser microdissection describes a method of precise cutting of tissue areas using a laser and the separation of the cut section from the surrounding tissue. There are different methods of laser dissection and to isolate target cells after cutting.
Laser microdissection: A powerful tool for genomics at cell level
2018年2月1日 · Laser microdissection (LM) has become widely democratized over the last fifteen years. Instruments have evolved to offer more powerful and efficient lasers as well as new options for sample collection and preparation.
Laser capture microscopy - PMC
This review concerns a recent advance in microdissection techniques, namely laser capture microdissection (LCM). The principle underlying this technique is outlined, and practical issues pertaining to LCM are considered.
Laser capture microdissection for biomedical research: towards …
2023年9月1日 · Laser capture microdissection (LCM) is a cutting-edge method for acquiring spatial information that can quickly collect regions of interest (ROIs) from heterogeneous tissues, with resolutions ranging from single cells to cell populations.
Laser capture microdissection: methods and applications
Laser microdissection is a nonmolecular, minimally disruptive method to obtain cytologically and/or phenotypically defined cells or groups of cells from heterogeneous tissues.
Laser Capture Microdissection | Thermo Fisher Scientific - US
Laser capture microdissection is an automated technique that enables isolation of specific cells from a mixed population under microscopic visualization. The Arcturus LCM systems use of dual lasers helps preserve the biological integrity of tissue.
Laser Capture Microdissection: Methods and Protocols - Springer
Provides practical methods and protocols involving tissue-based laser microdissection, ideal for labs around the globe; Fully updates and reexamines the popular first edition; Features key notes and expert implementation advice; Includes supplementary material: sn.pub/extras
Laser capture microdissection: Big data from small samples
Laser capture microdissection (LCM) is powerful to obtain a pure targeted cell subgroup, or even a single cell, quickly and precisely under the microscope, successfully tackling the problem of tissue heterogeneity in molecular analysis.
Application of genomic and proteomic technology to laser microdissected cells has revolutionized the classification of solid cancer and enhanced its diagnosis, prognosis and drug discovery.
Laser Capture Microdissection: From Genomes to Chromosomes, …
2023年6月20日 · Laser microdissection (LM) is a powerful tool for various molecular analyses providing pure samples for genomic, transcriptomic, and proteomic studies. Cell subgroups, individual cells, or even chromosomes can be separated via laser beam from complex tissues,...