Interferons Overview | Thermo Fisher Scientific - US
Learn about interferons (IFNs), a family of cytokines that modulate the immune response and inhibit viral replication. Find out the types, functions, induction, and antagonism of IFNs, and how to study them.
Regulation of type I interferon responses - Nature
2013年12月23日 · Type I interferons (IFNs) are polypeptides that are secreted by infected cells and have three major functions. First, they induce cell-intrinsic antimicrobial states in infected and...
IFNγ: signalling, epigenetics and roles in immunity ... - Nature
2018年6月19日 · IFNγ is a cytokine that is primarily produced by cells of the immune system, including innate-like lymphocyte populations, such as natural killer (NK) cells and innate lymphoid cells (ILCs),...
Interferon (IFN) Cell Signaling Pathway - Thermo Fisher Scientific
Induction of interferon (IFN) gene expression leads to increase cellular resistance to viral infection and may also affect cell growth. Two subtypes of interferons comprise the IFN family of cytokines.
Mechanisms of type-I- and type-II-interferon-mediated signalling …
2005年5月1日 · There are two main classes of interferon (IFN): type I IFNs and type II IFN. There are many type I IFNs, including IFN-α, IFN-β and IFN-ω, and all of these bind a common cell-surface receptor....
What Are Interferons (IFNs)? - Cleveland Clinic
Interferons are proteins that help your immune system fight infections and diseases. Learn about the different types of interferons, how they work, what conditions they treat and what side effects they may cause.
Interferon-gamma (IFN-γ): Reviewing its mechanisms and …
Interferon-gamma (IFN-γ) is a pleiotropic cytokine that plays a critical role in mediating an array of immune responses including promotes antiviral activity, facilitates macrophage activation, controls Th1/Th2 balance, and regulates cellular apoptosis and proliferation.
11.4B: Interferons - Biology LibreTexts
2024年11月23日 · Interferons (IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites, or tumor cells. IFNs belong to the large class of glycoproteins known as cytokines. Interferons are named after their ability to “interfere” with viral replication within host cells.
Interferon - an overview | ScienceDirect Topics
Interferon is a type of cytokine that activates antiviral proteins in host cells. Learn about the types, functions, and uses of interferon in neuroscience and infectious diseases.
Interferon-gamma (IFN-γ): Exploring its implications in infectious ...
2018年5月30日 · A key player in driving cellular immunity, IFN-γ is capable of orchestrating numerous protective functions to heighten immune responses in infections and cancers. It can exhibit its immunomodulatory effects by enhancing antigen processing and presentation, increasing leukocyte trafficking, inducing …
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