Physiology of gastric acid secretion - UpToDate
2022年11月28日 · This topic will review the mechanism and regulation of gastric acid secretion. The physiology of gastrin, somatostatin, and gastric acid hypersecretory states are discussed in detail separately.
胃酸分泌的生理学 - UpToDate
专题提纲. 总结; 引言; 胃的功能性解剖; 胃酸的作用和分泌的阶段. 头期; 胃期; 肠期; 胃酸和胃蛋白酶的调节. 胃酸 - 胃壁细胞的作用 - 刺激因子 胃泌素
Proton pump inhibitors: Overview of use and adverse effects in the ...
2024年5月31日 · Proton pump inhibitors (PPIs) effectively block gastric acid secretion by irreversibly binding to and inhibiting the hydrogen-potassium ATPase pump that resides on the luminal surface of the parietal cell membrane.
UpToDate
2023年3月20日 · Gastrin is the major hormonal regulator of gastric acid secretion . Its discovery in 1905 was based upon its profound effect on meal-stimulated acid secretion, making it one of the first hormones to be described .
胃泌素的生理学 - UpToDate
人前胃泌素原含有101个氨基酸(amino acid, AA)，包括一个信号肽(21AA)、间隔区序列(37AA)、胃泌素成分(34AA)和一个羧基端的扩展片段(9AA)。胃泌素所有已知的生理活性形式都产生于前胃泌素原的酶加工过程。
UpToDate
The H+ secreted into the gastric lumen by the H+-K+-ATPase combines with luminal Cl- to form gastric acid, HCl. Inhibition of the H+-K+-ATPase is the most efficacious method of preventing harmful gastric acid secretion.
VIPoma: Clinical manifestations, diagnosis, and management
2024年8月29日 · Physiology of gastric acid secretion; Society guideline links: Neuroendocrine neoplasms; Somatostatinoma: Clinical manifestations, diagnosis, and management; Surgical resection of lesions of the body and tail of the pancreas; Surgical resection of sporadic pancreatic neuroendocrine tumors
UpToDate
2022年7月27日 · Proton pump inhibitors (PPIs) effectively block gastric acid secretion by irreversibly binding to and inhibiting the hydrogen-potassium ATPase pump that resides on the luminal surface of the parietal cell membrane.
UpToDate
2021年11月2日 · Other biologic actions of VIP including vasodilation, inhibition of gastric acid secretion, bone resorption, and enhanced glycogenolysis are responsible for flushing as well as laboratory findings of hypochlorhydria, hypercalcemia, and hyperglycemia in …
Secretin - UpToDate - Wolters Kluwer
2023年3月15日 · It is now known that secretin stimulates pancreatic fluid and bicarbonate secretion leading to neutralization of acidic chyme in the intestine. Secretin also inhibits gastric acid release and intestinal motility.