Central sensitization, chronic pain, and other symptoms ...
2023年4月1日 · Central sensitization, a pathophysiologic process in which the central nervous system undergoes changes that alter its processing of pain and other sensory stimuli, may be the mechanism underlying various conditions in which patients have unexplained pain and fatigue.
Central sensitization syndrome: Diagnosis, symptoms, and more
2023年9月15日 · Central sensitization syndrome occurs when the CNS amplifies its response to sensory stimuli. It may play a role in chronic pain conditions.
Central Sensitivity Syndromes: Symptoms and Chronic Pain
2024年4月3日 · Central sensitization syndromes (CSS) are a collection of disorders where the central nervous system misfires and amplifies sensory input resulting in pain, fatigue, brain fog, and sleep problems. Fibromyalgia (FMS), chronic fatigue syndrome (ME/CFS), and other chronic pain conditions fall under the CSS description.
What is Central Sensitization? — Institute for Chronic Pain
2012年4月27日 · Central sensitization is a condition of the nervous system that is associated with the development and maintenance of chronic pain. When central sensitization occurs, the nervous system goes through a process called wind-up and gets …
What is central sensitization and how does it relate to pain?
2024年5月10日 · When you have central sensitization, your brain overreacts to sensory signals, treating them as though they indicate danger and sounding the alarm with subsequent physical reactions. Hyperexcitability of the central nervous system can occur even in the absence of sensory information coming from the peripheral nerves.
Central sensitization: Implications for the diagnosis and ...
Central sensitization is a robust phenomenon, readily induced in human volunteers in response to diverse ways of activating nociceptors (electrical stimulation, capsaicin, mustard oil, acid, heat burn, UV burn, hypertonic saline).
In central sensitization, the central nervous system under-goes structural, functional, and chemical changes that make it more sensitive to pain and other sensory stimuli. Central sensitization provides an explanatory framework for various frequently encountered conditions.
Central sensitisation: causes, therapies, and terminology
A growing evidence base is emerging to identify upstream risk factors of central sensitivity syndromes—including exposure to adversity, childhood maltreatment, and domestic abuse—that could be targeted through focused public health and primary care policies. 2,3 As Nijs and colleagues allude to, the lack of effective treatments for patients ...
Psychosocial Factors and Central Sensitivity Syndromes
Central sensitivity syndromes (CSSs) represent a heterogeneous group of disorders (e.g., fibromyalgia [FM], irritable bowel syndrome [IBS], chronic headache, temporomandibular disorders [TMDs], pelvic pain syndromes) that share common symptoms, with persistent pain being the most prominent feature.
Central means the problem is at the level of the brain and spinal cord. The neurons (brain and spinal cord cells) are “hyper-excitable” or sensi,zed because of changes in the way the cells communicate chemically and through other mechanisms.