α-Glucosidase - Wikipedia
Mechanism. α-Glucosidase hydrolyzes terminal non-reducing (1→4)-linked α-glucose residues to release a single α-glucose molecule. [10] α-Glucosidase is a carbohydrate-hydrolase that releases α-glucose as opposed to β-glucose. β-Glucose residues can be released by glucoamylase, a functionally similar enzyme.
Alpha-Glucosidase - an overview | ScienceDirect Topics
Alpha-glucosidase, a brush border enzyme that hydrolyzes starch and disaccharides to release glucose for absorption into the enterocyte, is another enzyme potentially involved in whey-mediated glucose lowering.
Alpha-Glucosidase - an overview | ScienceDirect Topics
Alpha-glucosidase is an enzyme that plays an important role in the absorption of glucose in the gastrointestinal tract. Inhibition of this enzyme activity can reduce blood glucose levels, preventing postprandial hyperglycemia in patients with type 2 diabetes mellitus.7.
Alpha Glucosidase Inhibitors - StatPearls - NCBI Bookshelf
2024年2月28日 · Alpha-glucosidase inhibitors inhibit the absorption of carbohydrates from the small intestine. They competitively inhibit enzymes that convert complex nonabsorbable carbohydrates into simple absorbable carbohydrates. These enzymes include glucoamylase, sucrase, maltase, and isomaltase.
Glucosidases - Wikipedia
Function. Alpha-glucosidases are enzymes involved in breaking down complex carbohydrates such as starch and glycogen into their monomers. [2] They catalyze the cleavage of individual glucosyl residues from various glycoconjugates including alpha- …
Alpha Glucosidase - an overview | ScienceDirect Topics
1999年5月4日 · α-Glucosidase is an exoenzyme acting in a manner similar to that of glucoamylase on di- and oligo-saccharides and aryl glucosides. It yields glucose. This enzyme can be of animal, plant, bacterial, or fungal origin.
α-Glucosidases and α-1,4-glucan lyases: structures, functions, and ...
2016年4月30日 · α-Glucosidase (AGase; EC 3.2.1.20) is a typical exohydrolase that reacts with the α-glucosidic linkage of the non-reducing terminal of substrates and releases α-glucose [1, 2]. Under high substrate concentrations, the enzyme also catalyzes transglucosylation, synthesizing oligosaccharides (Fig. 1a). AGases exist in most organisms, indicating ...
α-Glucosidases and α-1,4-glucan lyases: structures, functions, and ...
α-Glucosidases (AGases) and α-1,4-glucan lyases (GLases) catalyze the degradation of α-glucosidic linkages at the non-reducing ends of substrates to release α-glucose and anhydrofructose, respectively.
Molecular Mechanism in α -Glucosidase and Glucoamylase
1997年1月1日 · The hydrolysis of glucosidic linkage catalyzed by every carbohydrate-hydrolase is a reaction in which the product retains (α → α or β → β) or inverts (α → β or β → α) the anomeric configuration of the substrate. α -Glucosidase and glucoamylase are essentially distinguished by releasing α -glucose and β -glucose, respectively, from the common sub...
alpha-Glucosidases - PubMed
This review highlights the main properties of mammalian, plant, and microbial alpha-glucosidases. Special attention is given to the classification of these enzymes, possible catalytic mechanisms, their tertiary structure, and the structure of major inhibitors.