Psoriatic Arthritis - StatPearls - NCBI Bookshelf
2024年1月7日 · Psoriatic arthritis, occurring in approximately 20% of individuals with psoriasis, is a chronic inflammatory arthritis intricately linked to psoriatic arthritis. This aggressive condition is characterized by potential significant morbidity and compromised quality of life.
The pathogenesis of psoriatic arthritis - PubMed
2018年6月2日 · Psoriatic arthritis is a chronic, immune-mediated, inflammatory arthropathy that presents with inflammation of the joints and entheses, including those of the axial skeleton, and is associated with increased mortality from cardiovascular disease.
An overview of psoriatic arthritis – epidemiology, clinical features ...
This article gives an overview of the complexity of psoriatic arthritis, looking at several aspects of this heterogeneous disease, such as epidemiology, important clinical features and comorbidities as well as current concepts of the pathophysiology …
The Molecular Pathophysiology of Psoriatic Arthritis—The …
Psoriasis and psoriatic arthritis are multifactor disorders characterized by aberrant immune responses in genetically susceptible individuals in the presence of additional (environmental) factors, including changes in microbiota and/or epigenetic marks.
The pathogenesis of psoriatic arthritis
2018年6月2日 · Psoriatic arthritis is a chronic, immune-mediated, inflammatory arthropathy that presents with inflammation of the joints and entheses, including those of the axial skeleton, and is associated with increased mortality from cardiovascular disease.
Psoriatic arthritis - PMC
PsA is an inflammatory musculoskeletal disease associated with cutaneous psoriasis. It affects men and women almost equally with a peak age at onset of 40 and 50 years. It is a diverse disease that affects multiple organ systems includes …
Psoriatic arthritis: recent progress in pathophysiology and drug ...
2013年12月18日 · Pathophysiology of psoriatic arthritis In PsO and PsA, as in many autoimmune and autoinflammatory diseases, there is a complex interaction of genetic and environmental factors leading to a self-sustained and persistent immune response.
Pathogenesis of psoriatic arthritis - ScienceDirect
2021年6月1日 · Distinct clinical phenotypes of psoriatic arthritis (PsA) occur as a result of genetic predisposition, environmental triggers (such as biomechanical or metabolic stress, infections and obesity) and local factors according to the disease site (joints, skin, spine or entheses).
Psoriatic arthritis: update on pathophysiology, assessment and ...
Psoriatic arthritis (PsA) is classified as a spondyloarthropathy and characterised by synovitis, enthesitis, dactylitis and spondylitis usually manifesting as skin and nail psoriasis. Our understanding about the PsA disease state, its genetics, pathophysiology and comorbidities, as well as the abili …
Psoriatic Arthritis: Pathogenesis and Targeted Therapies
2023年3月3日 · In this narrative review, we aim to provide an updated overview of the pathophysiology, including the latest findings from multiomics studies, and to describe current targeted therapies.
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