COPD - What Is COPD? - NHLBI, NIH
2024年11月8日 · The term COPD refers to two main conditions: Emphysema develops when there is damage to the walls between many of the air sacs in the lungs. Normally, these sacs are elastic or stretchy. When you breathe in, each air sac fills up with air, like a small balloon. When you breathe out, the air sacs deflate, and the air goes out.
COPD - Alpha-1 Antitrypsin Deficiency - NHLBI, NIH
2023年10月25日 · Alpha-1 antitrypsin (AAT) deficiency increases an individual’s risk for COPD. The deficiency is an inherited genetic condition with no cure. The resulting COPD would be treated in the standard manner, with bronchodilators, steroids, pulmonary rehabilitation, oxygen therapy, and surgery. AAT is diagnosed with a blood test.
Model shows emphysema might be reversed with injection of …
When the researchers deleted the gene for LRG1 from lung endothelial cells in mice, the animals’ lungs were largely protected from the lung damage of induced emphysema, much as they had been by the endothelial cell therapy. The study was funded by NHLBI.
COPD - Symptoms - NHLBI, NIH
2024年10月4日 · Common symptoms of COPD include: Shortness of breath, especially with physical activity. You may feel like breathing takes more effort or that you are gasping for air. An ongoing cough or a cough that produces a lot of mucus , sometimes called a smoker’s cough. This is often the first symptom of COPD.
Bronchodilators don’t improve smoking-related respiratory …
2022年9月4日 · In the 12-week, randomized, double-blinded study, which was part of the Redefining Therapy in Early COPD for the Pulmonary Trials Cooperative (RETHINC), researchers enrolled 535 adults with symptoms of COPD, ages 40-80, at one of 20 U.S. medical centers. Twice each day, study participants used an inhaler that contained either medication or a ...
Bronchitis - Bronchitis - NHLBI, NIH
2022年12月2日 · Bronchitis is a condition that develops when airways in the lungs become inflamed and cause coughing, often with mucus, or wheezing. Acute bronchitis goes away after a few weeks but chronic, or long-term, bronchitis can be serious and last for at least three months. Learn more about symptoms, how to prevent, and treatment.
COPD, or chronic obstructive pulmonary disease, is a serious lung disease that over time makes it hard to breathe. Other names for COPD include chronic bronchitis or emphysema. COPD, a leading cause of death, afects millions of Americans and causes long-term disability. Most often, COPD occurs in people age 40 and over who...
COPD, or chronic obstructive pulmonary disease, is a serious lung disease that over time makes it hard to breathe. Other names for COPD include chronic bronchitis or emphysema. COPD, a leading cause of death, affects millions of Americans and causes long-term disability. Most often, COPD occurs in people age 40 and over who...
COPD - Causes and Risk Factors | NHLBI, NIH
2024年10月4日 · Most people who have COPD are at least 40 years old when symptoms begin. A condition that runs in families, called alpha-1 antitrypsin (AAT) deficiency: If you are born with this condition, smoking or long-term exposure to fumes or dust can lead to lung damage and COPD. AAT deficiency can also raise your risk for developing COPD at a younger age.
What Are Interstitial Lung Diseases? - NHLBI, NIH
2022年3月24日 · Español. Interstitial lung diseases (ILDs) are a group of several disorders that can cause scarring in your lungs. The scar tissue in your lungs affects your lungs’ ability to carry oxygen and can make it harder for you to breathe normally. In ILDs, scarring damages tissues in or around the lungs’ air sacs, or alveoli, and airways.