Growth hormone | C78H110N22O30S6 | CID 170907453 - PubChem
Growth hormone, also known as somatotropin, stimulates mitosis, cell differentiation and cell growth. Species-specific growth hormones have been synthesized.
Growth hormone - Wikipedia
GH is a 191- amino acid, single-chain polypeptide that is synthesized, stored and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland. A recombinant form of HGH called somatropin (INN) is used as a prescription drug to treat children's growth disorders and adult growth hormone deficiency.
Somatotropin (32-38) | C39H60N8O13 | CID 126658 - PubChem
Somatotropin (32-38) | C39H60N8O13 | CID 126658 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
1HGU: HUMAN GROWTH HORMONE - RCSB PDB
1995年5月11日 · THE CRYSTAL-STRUCTURE OF WILD-TYPE GROWTH-HORMONE AT 2.5 ANGSTROM RESOLUTION. Biological Assembly 1. Explore in 3D: Structure | Sequence Annotations | Electron Density | Validation Report. Biological assembly 1 assigned by authors.
Growth hormone isoforms and segments/fragments: Molecular structure …
2006年2月1日 · The structure–function relationship is of particular importance for multifunctional protein hormones such as growth hormone (GH). For clinical diagnosis, it is imperative to understand the relationship between GH structure (and its molecular fragments) and function and their potential interaction with single or multiple receptors.
Growth hormone, human | C72H132 | CID 168009821 - PubChem
2021年10月14日 · A polypeptide that is secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Growth hormone, also known as somatotropin, stimulates mitosis, cell differentiation and cell growth. Species-specific growth hormones have been synthesized.
Molecule of the Month: Growth Hormone - RCSB: PDB-101
Growth hormone brings together two copies of its cellular receptor. Human growth hormone (top left), prolactin (top right), and insulin-like growth factor (bottom). As children grow, their height, weight and strength increase. Numerous factors influence this growth, including the genetic makeup of the child, nutrition and environmental factors.
RCSB PDB - 3HHR: HUMAN GROWTH HORMONE AND …
Examination of the 2.8 angstrom crystal structure of the complex between the hormone and the extracellular domain of its receptor (hGHbp) showed that the complex consists of one molecule of growth hormone per two molecules of receptor. The hormone is a four-helix bundle with an unusual topology.
Growth Hormones: Expression, Structure and Protein Engineering …
The growth hormones (GHs) are polypeptide hormones with molecular weight of 22 kD consisting of one chain. GHs are synthesized in an anterior lobe of hypophysis as a precursors with molecular weight of 25 kD. These hormones are necessary for the normal growth and development of organism and play an essential role in regulation of anabolic ...
Structure and Regulation of the Human Growth Hormone-Releasing Hormone ...
1998年2月1日 · We investigated structure and regulation of the human GHRH-R gene. A genomic clone including approximately 12 kb of 5′-flanking region was isolated. The gene is of complex structure consisting of more than 10 exons. Two kilobase pairs of the promoter were sequenced, and putative transcription factor binding sites were identified.