How to Use Low-Dose Atropine to Slow Myopic Progression in Kids
2016年12月1日 — Low-dose atropine (0.01%) has emerged as an effective approach, as highlighted by the Atropine in the Treatment of Myopia studies (ATOM1 and ATOM2). 3-7 Although ATOM enrolled Asian patients, studies are now under way involving other populations.
Low-Dose 0.01% Atropine Eye Drops vs Placebo for Myopia Control
We found that nightly low-dose atropine, 0.01%, eye drops did not slow myopia progression or axial elongation when compared with placebo over 24 months in a cohort of US children aged 5 to 12 years with spherical equivalent myopia of −1.00 to −6.00 D.
Low-Dose Atropine to Slow Myopia: Evidence and Adoption Are Growing
2021年8月1日 — Ophthalmologists are finding that the 0.01% concentration is optimal as a starting dose, said Jennifer A. Galvin, MD, FAAP, at Yale School of Medicine in New Haven, Connecticut. Starting dose. Dr. Galvin has been using 0.01% atropine eyedrops with her patients since 2014, based upon findings from ATOM2.
Atropine, 0.01%, for Myopia Control | Ophthalmology | JAMA ...
Atropine, 1%, eye drops have long been available for cycloplegia and was the original dose studied for myopia control, but more recently, much lower concentrations have been investigated to slow myopia progression while minimizing rebound effects (loss of accrued benefit after discontinuing treatment) and adverse effects such as photophobia and ...
Low-dose atropine eyedrops no better than placebo for slowing …
2023年7月13日 — Use of low-dose atropine eyedrops (concentration 0.01%) was no better than placebo at slowing myopia (nearsightedness) progression and elongation of the eye among children treated for two years, according to a randomized controlled trial conducted by the Pediatric Eye Disease Investigator Group (PEDIG) and funded by the National Eye Institute ...
Efficacy and Safety of 8 Atropine Concentrations for
2021年6月12日 — Higher-dose atropine ranked as a better intervention in slowing down refraction changes and axial elongation than did lower-dose atropine. Among moderate-dose atropine (0.02%–0.25%), 0.05% showed efficacy comparable with that of high-dose atropine and was ranked third in terms of retarding refraction changes and second in slowing down axial ...
Which low‐dose atropine for myopia control? - PMC
2019年9月5日 — Recent findings show that low‐dose atropine, if used in concentrations higher than 0.01%, can offer considerable slowing of myopia progression and also reduced eye growth.4 Both 0.025% and 0.05% atropine slow eye elongation significantly over one year (0.025%: 0.12 mm, 29.3 per cent, and 0.05%: 0.21 mm, 51.2 per cent, relative to placebo ...
Growing Body of Research Suggests Low-Dose Atropine Can …
2023年11月5日 — The analysis shows that a low-dose, preservative-free formulation of atropine is effective in slowing progression in children aged 3 to 17, living in the U.S. and European Union. The children had between −0.50 D to −6.00 D spherical equivalent refraction, and received daily placebo or a proprietary formulation of low-dose atropine.
Low concentration atropine and myopia: a narrative review of the ...
2023年9月16日 — Concentration and physiochemical stability of low dose atropine is a key target when ensuring effective, repeatable and stable dosing for children receiving low dose atropine treatment.
Effect of low-dose atropine on myopia progression, pupil …
Many studies have shown that moderate and low concentrations of atropine (eg, 0.01%, 0.025%, 0.05%, 0.1%) could control the progression of myopia in children with reasonable efficacy, minimal side effects, convenient use and slight rebound effects after discontinuation. 4–6 17 However, there are differences in the efficacy and side effects ...
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