Objective To compare the treatment efficacy and safety of tofacitinib (TOF) versus methotrexate (MTX) in Takayasu arteritis (TAK). Methods Fifty-three patients with active disease from an ongoing ...

Background: Glucocorticoids (GC) are the cornerstone of the treatment of polymyalgia rheumatica (PMR) and giant cell arteritis (GCA), but they are associated with several adverse events (AEs).

11 University of Pennsylvania, Division of Epidemiology, Department of Biostatistics, Epidemiology, and Informatics, Philadelphia, PA, United States of America 12 University of Pennsylvania, Division ...

Objectives Nerve growth factor (NGF) has emerged as a key driver of pain in osteoarthritis (OA) and antibodies to NGF are potent analgesics in human disease. Here, we validate a novel vaccine strategy ...

Methods SFs from 38 gouty patients were analysed for white blood cell (WBC) count, percentage of polymorphonuclear cells (PMNs) and levels of interleukin 1β (IL-1β), IL-6, IL-8, tumour necrosis ...

Correspondence to Alberto Martini, University of Genoa, Pediatria II, Istituto G Gaslini, Largo Gaslini 5, Genova 16147, Italy; albertomartini{at}ospedale-gaslini.ge.it Juvenile idiopathic arthritis ...

2 Department of Orthopaedic Surgery (RKU), University of Ulm, Germany 3 Department of Internal Medicine II—Cardiology, University of Ulm, Germany Correspondence to: Dr T Stürmer Department of ...

Background: About 20% of individuals in the USA have asymptomatic hyperuricaemia [1]. However, Urate-lowering therapy in asymptomatic hyperuricaemia condition is still controversial considering the ...

Introduction Genome-wide association studies of multiple autoimmune diseases, including Sjögren’s syndrome, systemic lupus erythematosus and rheumatoid arthritis have identified associations in the ...

Background: Individuals with autoimmune rheumatic diseases (ARDs) that are receiving treatment with rituximab (RTX) are at higher risk of severe outcomes upon infection with SARS-CoV-2 [1,2]. However, ...