During this process of transcription, the cell may make mistakes in the mRNA’s sequence and based on it produce faulty ...

enables precise multiomic characterization of biomolecular interaction networks at target RNAs. Distinct O-MAP workflows reveal RNA-adjacent proteins, transcripts and genomic loci.

Transcriptomics data, obtained through RNA sequencing (RNA-seq), offer a detailed landscape of lncRNA expression profiles across different tissues and stages of cancer. This data can identify ...

Working in the German college town of Tubingen, Stafforst and fellow researchers at the local university were instead engrossed by the prospect of rewriting RNA, DNA’s chemical cousin. “Everybody told ...

On the other hand, DNA damage responses, including replication stress and ATR, serve a positive role at telomeres, acting as a trigger for recruitment of the telomere-elongating enzyme telomerase to ...

记者10月10日从中山大学获悉，中山大学医学院施莽教授团队与阿里云李兆融团队在《细胞》杂志（Cell）发表的论文报告了全球范围的180个超群、16万余种的RNA病毒发现，大幅扩展了全球RNA病毒的多样性。 该研究将人工智能技术应用于病毒鉴定，发现了传统研究 ...

上世纪90年代，美国科学家维克托·安布罗斯和加里·鲁夫坎找到了“生命指南”的关键——微小核糖核酸（微小RNA）及其在转录后基因调控中的作用 ...

Researchers say they have successfully completed a trial of a personalised cancer vaccine that uses the same messenger-RNA technology as Covid jabs. The experimental vaccine, made by Moderna and ...

With the persistent presence of intronic sequences, cryptic and aberrant splicing become more likely, and cryptic exon inclusions in AU-rich introns will in many cases contain PAS-signal and thus ...

We dissected the importance of human telomerase biogenesis and trafficking pathways for telomere maintenance. Biological stability of human telomerase RNA (hTR) relies on H/ACA proteins, but other ...