Our findings reveal that ciliary CDC42, a RHO-family GTPase triggers in situ actin polymerization, ciliary ectocytosis, and cilia shortening in BBSome-deficient cells. Activation of the Sonic Hedgehog ...

Mitogen-activated protein kinase (MAPK) is a class of protein kinases that are activated in response to a variety of external signals ... the nanotechnology-based renal tubule-targeted drug delivery ...

Figure 1. Systemic and brain distribution of GPR37. GPR37 is expressed in various cell types, including vascular smooth muscle cells, macrophages, alveolar and renal tubular epithelial cells, ...

2 Limbal stem cell deficiency (LSCD) is a sight-threatening condition resulting in corneal opacity due to damage to the corneal surface from infections, immune disorders, chemicals, burns, or other ...

THE earliest lesions of certain types of experimental nephrocalcinosis involve the distal portions of the renal tubules ... of Cells Associated with Calcium Casts in the Tubular Lumen (X135).

How epithelial cell behaviors are coordinately regulated to sculpt tissue architecture is a fundamental question in biology. Kupffer’s vesicle (KV), a transient organ with a fluid-filled lumen, ...

We developed computational and experimental approaches to quantify, with both sub-cellular and multi-cellular resolution, the dynamics of force transmission in cell clusters. Applying this technology ...