Protein structure predictions are bioinformatic analyses that produce predicted protein structures automatically using the protein amino acid sequence. Protein structures are important because ...

In this way, the allosteric network generated by ligand binding is directly transferred to the G-protein binding sites. In conclusion, through a computational approach involving molecular dynamics ...

"The images show MP wrapping itself around five ... her team to think of MP as an octopus armed with tentacle-like proteins: "The body of the octopus is sitting on the bottom of the hairpin ...

From a different angle: Images of jets of charged particles emerging at ... A new imaging technique that takes standard two-dimensional (2D) radio images and reconstructs them as three-dimensional (3D ...

Cradle Bio B.V., a platform that accelerates the discovery of proteins using generative artificial intelligence models, announced today that it has raised $73 million to expand its lab and workforce.

Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON M5S 3E1, Canada Department of Computer Science, University of Toronto, Toronto, ON M5S 3E1, Canada Department ...

However, the F protein has a delicate structure that changes rapidly from a "pre-fusion" form to a "post-fusion" form when the viruses fuse with cells. Ideally, a vaccine would teach the immune ...

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RNA-protein interactions (RPIs) are promising targets for developing new molecules of ... a ‘pocket-’ased” pharmacophore screening built from the prediction of a pseudo-ligand in the binding site of ...

By debranching ubiquitin chains composed of K48 linkages, the proteasome-associated ubiquitin C-terminal hydrolase UCHL5/UCH37 serves as a positive regulator of protein degradation. How UCH37 achieves ...

The latter fibril was resolved at 8 Å resolution showing pairs of β-sheets at the cores of the two protofilaments making up a fibril. Detailed comparison of the Aβ(1–42) and Aβ(1–40) fibril structures ...