Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The mevalonate pathway produces essential ...

德国Max delbrck中心Michael Sigal实验室和柏林慈善医院的研究人员在《科学进展》杂志上发表了一项研究结果，阐明了p53基因在溃疡性结肠炎中的作用，提出了一种潜在的新药靶点，可以阻止疾病发展为癌症。 由Max delbrck中心柏林医学系统生物学研究所（MDC-BIMSB ...

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Researchers have elucidated the role of the p53 gene in ulcerative colitis. The study suggests a potential new drug target to stop disease progression to cancer. Researchers in the lab of Michael ...

Researchers in the lab of Michael Sigal at the Max Delbrück Center and Charité—Universitätsmedizin Berlin have elucidated the role of the p53 gene in ulcerative colitis. The study ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Senescent cells present an excessive flux of ...

qPCR analysis shows the level of p53 mRNA in H1299-R175H cells 24 hours after transfection with dp53m (l). PAGE electrophoresis indicates the serum stability of dp53m (m, n). This study was led by ...

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York. *Corresponding Author: Marc Ladanyi, Department of Pathology and Laboratory Medicine, Memorial ...

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p53 lies at the hub of a vast signalling network. Polymorphisms in upstream activators, repressors or downstream effectors of p53 might individually modulate cancer risk or interact with ...