The damage caused by Alzheimer's disease begins long before any symptoms show up. Over the course of years or decades in this preclinical stage, the characteristic buildup of disease-causing amyloid ...
Alzheimer’s is caused by specific brain changes called amyloid plaques and neurofibrillary tangles. However, FTD is actually a group of different diseases with various causes. This makes it ...
Veravas, Inc., a leading innovator in clinical diagnostics, today announced a collaboration with Phanes Biotech to co-develop a blood-based Alzheimer’s disease (AD) tau pathology test. Phanes Biotech ...
The MAPT transgene is driven by the rat Prnp promoter. Overexpress the 0N4R isoform of human tau with the P301S mutation Homozygotes develop neurofibrillary tangles, exhibit neurodegeneration, and die ...