Since most of the patients included in these studies were critically ill and may have received several potentially nephrotoxic drugs simultaneously, it may not be appropriate to implicate colistin ...

In clinical practice, strategies to reduce nephrotoxicity due to specific drugs are usually based on the avoidance of established risk factors, such as high doses. However, effective prevention of ...

One in ten adults suffer from chronic kidney disease (CKD), a condition characterized by progressive loss of kidney function.

This frequently manifests during drug development and/or in standard clinical care. Nephrotoxicity resulting from drug exposure has been estimated to contribute to 19–25% of all cases of acute ...

Caution with immunosuppressants (eg, cyclosporine), other nephrotoxic drugs. Abnormal liver function tests, elevated CPK, respiratory or GI effects, myopathy, cholelithiasis, pancreatitis ...

Increased toxicity with nephrotoxic drugs (eg, NSAIDs). Increased risk for blood disorders, bone marrow failure, and associated complications with azathioprine or 6-mercaptopurine and/or other ...

Drug-induced nephrotoxicity is a significant concern, accounting for up to 60% of acute kidney injury (AKI) cases in ...