PROG (initiated within 4 h of injury and administered for 72 h, followed by an additional 24-h taper) versus placebo for treating victims of moderate-to-severe acute TBI (GCS score of 12-4).

Researchers have investigated if correlations exist between variables in the acute stage of injury and outcome measures in TBI patients. The Glasgow Coma Scale (GCS) score is one variable that was ...

The study included 49 patients with severe TBI and a Glasgow Coma Scale score of ≤8. Thirty-six patients received one or two 24 h infusions of ciclosporin, and 10 patients received placebo ...

brainstem and respiration), each of which has a maximal score of 4. In contrast to the GCS, verbal response is not a component of the FOUR score, making it fully applicable in intubated patients.