Innate lymphoid cells (ILCs) are immune cells that belong to the lymphoid lineage but do not express antigen-specific receptors. These cells have important functions in innate immune responses to ...

Nivolumab is under clinical development by Bristol-Myers Squibb and currently in Phase II for Paranasal Sinus And Nasal Cavity Cancer.

Nivolumab is under clinical development by Bristol-Myers Squibb and currently in Phase II for Osteosarcoma. According to GlobalData, Phase II drugs for Osteosarcoma have a 13% phase transition success ...

Barrett's esophagus usually develops in the context ... the damaged mucosa is replaced with a more acid- and bile-resistant epithelium. The prevailing view is that acid and bile in the refluxate ...

The airways mediate the transport of inhaled air to the lungs and are lined with a layer of epithelial cells that provide protection against inhaled pathogens. In respiratory diseases such as primary ...

[66,82] The molecular signature of normal squamous esophageal epithelium identifies the presence of a field effect and can discriminate between patients with Barrett's esophagus and patients with ...

The result showed that the AKR1B10 highly expressed in stomach and bladder, followed by esophagus, colon, liver, skin and adrenal gland, and AKR1B10 is barely expressed in brain and lymph node (Figure ...

Epithelial cells that line the inner layer of the intestine tract supply a barrier for entrance of pathogenic microbes. In addition, epithelial cells actively contribute to pathogenesis of IBD by ...

Increased intestinal permeability has been described in these patients, especially in the proximal small bowel or duodenum, and was associated with mucosal immune activation and symptoms. In this ...