Johns Hopkins University School of Medicine and Johns Hopkins Kimmel Cancer Center researchers Stephen Baylin, M.D., and Andrew Feinberg, M.D., were ...
SOX-OCT binding site and CTCF binding site 3 in H19-ICR are the sequences in which mutations cause H19-ICR hypermethylation leading to Beckwith-Wiedemann syndrome-like overgrowth. DNA methylation ...
This study would be of interest to biologists in the fields of epigenetics and metabolism. Maternal obesity has deleterious effects on the process of establishing oocyte DNA methylation; yet the ...
As an oncometabolite, R-2-HG induces malignant transformation of glial progenitor cells by altering the chromatin structure (through broad DNA and histone hypermethylation) and disrupting the ...
DNA methylation is a fundamental modification characterized by the addition of a ... By analyzing 571 PTC samples from The Cancer Genome Atlas (TCGA), the researchers found that patients with TERT ...
It started with a finger bone found in a cave in the Altai mountains in Siberia in the late 2000s. Thanks to advances in DNA analysis, this was all that was required for scientists to be able to ...
Human genome sequencing methods. (NIH) These overlooked genes have been hiding away in regions of our DNA thought not to code for proteins. These regions were once dismissed as 'junk DNA' but it turns ...