For the study, scientists at Gladstone Institutes in the US created a "chimeric" mice model for studying Alzheimer's. The mouse model not only carries human APOE genes, but the team also transplanted ...
In healthy brains, immune cells called microglia patrol for damage, clearing away debris and harmful proteins. But in the presence of the APOE4 protein-;the most important genetic risk factor for ...
Lipids Open the Door. Microglial cells treated with unlipidated (top) or lipidated (bottom) ApoE (yellow) along with fluorescently tagged Aβ (green). Lipidated ApoE was more readily internalized and ...
Taurine may decrease atherosclerotic plaque size and enhance vascular stability, as shown in studies on humans and mice. Previous research has suggested that taurine supplementation could help slow ...