Determining severity of illness and undertaking an adequate risk assessment is a fundamental part of acute paediatric practice. This review highlights physiology, communication, heuristics and ...

This review provides an overview of the use of antihistamines in children. We discuss types of histamine receptors and their mechanism of action, absorption, onset and duration of action of ...

1 Department of Paediatric Surgery, Great Ormond Street Hospital for Children, London, UK 2 Department of Paediatric Surgery, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK Correspondence to ...

Next generation sequencing (NGS), massively parallel or deep sequencing are related terms that describe a DNA sequencing technology which has revolutionised genomic research. Using NGS an entire human ...

Necrotising enterocolitis (NEC) in preterm babies is a serious gastrointestinal emergency with potentially devastating consequences. Prompt and accurate diagnosis continues to be a challenge for ...

While the majority of lesbian, gay, bisexual and transgender (LGBT) adolescents, much like their cis-gendered heterosexual peers, will be confident and healthy young individuals, there are well-known ...

Hyperkalaemia can lead to life-threatening cardiac arrhythmias. A good understanding of the physiological basis of management can help us rationalise treatment and reduce plasma potassium levels ...

1 Guy’s, King’s & St Thomas’ School of Medicine, Kings College London, London, UK 2 University Hospital Lewisham, NHS Trust and Guy’s & St Thomas’ Hospital NHS Foundation Trust, London, UK 3 South ...

2 Department of Neurology, Room 146, Atkinson Morley Wing, St Georges Hospital, Blackshaw Rd, London Correspondence to Mary Robertson, Department of Neurology, Room 146, Atkinson Morley Wing, St ...

Correspondence to Dr Miriam Fine-Goulden, Paediatric Intensive Care, Evelina London Children"s Hospital, London SE1 7EH, UK; miriam.finegoulden{at}gstt.nhs.uk As for any metabolite, blood lactate ...

Tremor is defined as a rhythmic, involuntary, oscillatory movement of body parts. Although constituting nearly 20% of presentations with paediatric movement disorders, tremor in childhood, beginning ...

Correspondence to Dr Andrew James McArdle, Department of Infectious Disease, Imperial College London, London W2 1NY, UK; andrew.mcardle{at}gmail.com Proteomics is the study of a large number of ...