LPX-TI641 is an oral novel Treg-expanding T cell/transmembrane, immunoglobulin, and mucin (Tim)receptor agonist therapy in development for the ...

A charged amino acid side chain close to the center of Orai1-transmembrane domain (TM)3 or -TM4 triggers robust constitutive activity due to enhanced hydration and widening of peripheral TM ...

Crystal structures of a mammalian multidrug efflux pump bound to peptide inhibitors may reveal drug-binding sites. Figure 1: Ribbon renditions of the structure of P-glycoprotein embedded in a ...

CREATE DOMAIN creates a new domain. A domain is essentially a data type with optional constraints (restrictions on the allowed set of values). The user who defines a domain becomes its owner. If a ...

Trump Names Scott Bessent as His Pick for Treasury Secretary The billionaire hedge fund manager would be responsible for steering President-elect Trump’s unconventional economic agenda. Kennedy ...

BOSTON, Nov. 18, 2024 /PRNewswire/ -- Sionna Therapeutics, a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF) by ...

This valuable study examines the effects of side-wall confinement on the chemotaxis of swimming bacteria in a shallow microfluidic channel. The authors present solid experimental evidence, combined ...

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