Fred Hutch researchers have done pioneering work in the areas of gene regulation, chromatin organization and cell cycle state, including quiescence. Gene expression is important because a specific ...

Gene regulation refers to the mechanisms that act to induce or repress the expression of a gene. These include structural and chemical changes to the genetic material, binding of proteins to ...

A collaborative effort between Mount Sinai and Memorial Sloan Kettering Cancer Center has shed valuable light on how ...

The course explores gene regulation in eukaryotes from nuclear organisation to cytosolic control, with a focus on animals and humans. The molecular mechanisms of transcription within a chromatin ...

GET decodes the “grammar” of genes, revealing how they are activated or deactivated, ultimately influencing the proteins our ...

the relatively simple mechanisms of gene expression in prokaryotic cells, as exemplified by the trp and lac operons, provide insight into several general principles involved in regulation in ...

When gene regulation fails, or specific genes are altered ... colloquially known as the fruit fly, because of its simple genetics and the fact that its genetic elements are incredibly similar ...

Along our journey, we shall reveal basic principles of gene regulation. We aim to exploit the new knowledge to help devise novel treatments of many diseases that stem from misregulated gene ...