Rho inhibition. Y27632, a selective Rho kinase (ROCK) inhibitor (Tocris, Ellisville, MO) was added to cells at a concentration of 20 μM/mL, 1 h before stretch and maintained throughout the ...
BioAxone’s broad pipeline of drugs targets different points in Rho/Rho kinase (ROCK) signaling and related pathways, which play key roles in serious conditions such as spinal cord injury ...
来自MSN5 个月
Targeting TGFβ/ROCK2/YAP signaling axis to enhance drug delivery in fibrotic pancreatic cancer"Initially, we assessed the impact of blocking the transforming growth factor-β (TGFβ) and Rho-associated kinase (ROCK) pathways on ECM remodeling and tissue permeability within our 3D fibrotic ...
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