This important paper takes a novel approach to the problem of automatically reconstructing long-range axonal projections from stacks of images. The key innovation is to separate the identification of ...

New research shows that the neural circuit responsible for stabilising gaze can develop in the absence of motor neurons, contrary to a long-standing model in the field.

Researchers led by the University of California, Irvine are the first to reveal how two neural circuits located in the ...

In examining the distribution of related cell types across structures, the researchers found that projection neurons — which send long-range connections elsewhere in the brain — are more ...

Researchers have identified a key biochemical mechanism relevant to the development of Huntington's Disease. This discovery ...

Locally connected "interneurons" are an integral part of the cortical circuit, reciprocally linking cortical neurons. Long-range "projection neurons," on the other hand, primarily populate ...

In the study, Surmeier and a team of Northwestern Medicine scientists set out to understand how spiny projection neurons—the principal neurons in the striatum, a key part of the brain circuitry ...

Researchers uncover a link between impaired glutathione–ascorbate metabolism and early dopamine increases in Huntington's ...

Researchers have identified a crucial biochemical mechanism that could allow Huntington’s disease to be studied before symptoms appear, offering hope for early intervention.