概述：PAMAM Dendrimer G5-SA（琥珀酸修饰的第五代PAMAM树枝状聚合物）是一种在第五代PAMAM聚合物基础上表面修饰了琥珀酸基团的分子。琥珀酸（SA）是一种二羧酸，通过连接到PAMAM分子表面上的氨基，形成新的羧基结构。这种修饰使PAMAM聚合物表面带有更多的羧基 ...

Osteoarthritis (OA) is the most common type of arthritis characterized by progressive cartilage degradation, with its pathogenesis closely related to chondrocyte autophagy. Chondrocytes are the only ...

Nanomedicine. 2012;7(8):1225-1233. Most of the strategies described for the passage of drugs across the BBB can be enhanced by nanotechnology and some of the mechanisms involved include: NPs open ...