Researchers have elucidated the role of the p53 gene in ulcerative colitis. The study suggests a potential new drug target to stop disease progression to cancer. Researchers in the lab of Michael ...

Researchers in the lab of Michael Sigal at the Max Delbrück Center and Charité—Universitätsmedizin Berlin have elucidated the role of the p53 gene in ulcerative colitis. The study ...

德国Max delbrck中心Michael Sigal实验室和柏林慈善医院的研究人员在《科学进展》杂志上发表了一项研究结果，阐明了p53基因在溃疡性结肠炎中的作用，提出了一种潜在的新药靶点，可以阻止疾病发展为癌症。 由Max delbrck中心柏林医学系统生物学研究所（MDC-BIMSB ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Senescent cells present an excessive flux of ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The mevalonate pathway produces essential ...

aDepartment of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way, Jupiter, FL 33458, United States bRobert and Arlene Kogod Center on Aging, Mayo Clinic, 200 ...

POLK expression in neurons and report an important observation that POLK exhibits an age-dependent change in subcellular localization, from the nucleus in young tissue to the cytoplasm in old tissue.