Researchers have revealed the role of enzyme TYK2 in the aggregation of tau proteins, which contributes to Alzheimer’s ...

SignalChem Biotech provides diverse recombinant Tau proteins for research, helping advance tau-targeted therapies that may ...

The MAPT transgene is driven by the rat Prnp promoter. Overexpress the 0N4R isoform of human tau with the P301S mutation Homozygotes develop neurofibrillary tangles, exhibit neurodegeneration, and die ...

Discover whether it's possible to have mixed dementia, specifically a combination of Alzheimer's and Lewy body dementia. This ...

Dementia, a term encompassing a decline in cognitive function, is a complex and often misunderstood condition. More than 55 ...

Taking Out OGA. The rationale behind small-molecule OGA inhibition is that these drugs will decrease tau hyperphosphorylation ...

The damage caused by Alzheimer's disease begins long before any symptoms show up. Over the course of years or decades in this preclinical stage, the characteristic buildup of disease-causing amyloid ...

Aneuro provides high-quality Tau products — proteins, fibrils, cell lines, and antibodies. These products assist researchers ...

LY3372689 was designed to slow the accumulation of hyper-phosphorylated, insoluble tau aggregates in the central nervous system, which clump together to form neurofibrillary 'tangles', one of the ...

The following is a summary of “Cerebral Amyloid Angiopathy, Dementia, and Alzheimer Neuropathologic Changes: Findings From ...