Peptides have emerged as a focal point in molecular and biological research, providing a promising avenue for understanding ...

As a leader in muscle biology and the mechanics of muscle performance, the company is developing small molecule drug candidates specifically engineered to impact myocardial muscle function and ...

Mechanisms accounting for in vivo inotropic effects of NO include parasympathetic and sympathetic outflow to the heart, myocardial cholinergic and adrenergic receptor-effector coupling, myocardial ...

Enhanced External Counterpulsation (EECP) is a unique outpatient, noninvasive treatment method currently used to improve myocardial ... that increases the heart's contractility by draining ...

The patient presented elevated FT4 levels. However, the cardiovascular manifestations of hyperthyroidism may occur due to minimal changes in hormone levels and include an increased heart rate at rest, ...

Cardiac remodelling is a complex process involving changes in cardiomyocytes and in the interstitium that results in progressive structural and functional alterations, including cardiac dilatation, ...

and cardiac remodeling leading to impaired contractility warrants further investigation. Public health experts seeking to reduce vaping‐related health risks should consider messaging that highlights ...

SOUTH SAN FRANCISCO, Calif., Dec. 20, 2024 (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced that Sanofi will acquire exclusive rights to develop and commercialize ...

Istaroxime is designed as a positive inotropic agent that increases myocardial contractility through inhibition of Na+/K+- ATPase with a complimentary mechanism that facilitates myocardial ...

Istaroxime is a first-in-class dual-mechanism therapy designed to improve both systolic and diastolic cardiac function. Istaroxime is designed as a positive inotropic agent that increases myocardial ...

Clinical manifestation is widely variable, including asymptomatic or mild respiratory tract illness to severe pneumonia and death. Myocardial injury is a significant pathogenic feature of COVID-19 and ...