Single-cell analysis of CML patients bone marrow at diagnosis reveals coexistence of CD26-CD35+ healthy stem cells and CD26+CD35- CML stem cells, and how the ratio between these impacts TKI response.
During the peer-review process the editor and reviewers write an eLife assessment that summarises the significance of the findings reported in the article (on a scale ranging from landmark to useful) ...
Ascentage Pharma (6855.HK), a global biopharmaceutical company engaged in discovering, developing, and commercializing therapies to address global unmet medical needs primarily for malignancies, today ...
With more than 30 different types, non-Hodgkin's lymphoma can even confuse doctors. This WebMD slideshow can help you learn more about what it is, the difference between B-cell and T-cell ...
How lactate has affected immunity in lymphoma is well worth exploring. The latest advances in single-cell technology, such as single-cell RNA sequencing (scRNA-Seq) and time-of-flight cytometry (CyTOF ...
T cells for ALL and lymphoma and immune checkpoint inhibitors (ICPIs) for lymphoma (2). In the past decade, we have made significant progress in understanding the biology of acute myeloid leukemia ...
Haematopoietic stem cells are progenitor cells that have the ability to both generate all types of blood cells, including those of the myeloid and lymphoid lineages, and to replace themselves.
This new experimental platform showed a superior ability to produce and sustain a balanced immune cell population, accurately representing the lymphoid and the myeloid immune lines. Also ...