Research indicates that cannabis use causes cellular damage that increases the risk of highly cancerous tumors by disrupting ...

In this study, our results uncover the function and mechanism of CHMP5 in the regulation of cell senescence and bone formation in osteogenic cells. Deletion of Chmp5 causes endolysosomal dysfunction ...

Mitochondria play a crucial role in immune signaling pathways by releasing danger-associated molecular patterns (DAMPs), like reactive oxygen species (mtROS), ATP, and mitochondrial DNA(mtDNA), which ...

Cannabis exposure leads to genetic damage and accelerated aging, raising concerns about its transgenerational health effects ...

Reactive oxygen species (ROS) from mitochondria are key drivers of genetic chaos in cancer by causing the collapse of micronuclear envelopes, a process that fuels the chromosomal instability (CIN) ...

Alcohol exacerbates insulin resistance, mitochondrial dysfunction, and oxidative stress ... PPARα = peroxisome ...

MitoThrive is a new doctor-formulated anti-aging supplement created by MD/PROCESS. Available exclusively online, MitoThrive ...

Because reactive oxygen species are produced via oxidative phosphorylation during anaerobic glycolysis, via the Schiff reaction during glycation, via glucose autoxidation, and via hexosamine ...

This study presents important findings on cold tolerance shared between hibernating and non-hibernating mammals, identifying a key molecule, GPX4, through multi-species genome-wide CRISPR screens. The ...

Huntington Medical Research Institutes (HMRI), a pioneer in scientific research with a track record of groundbreaking ...

In 2023, we published another article about CRSP in Cell Biology Education – A Journal of Life Science Education. That article assesses the impact of shifting research modalities and their impacts on ...

Here the authors developed and experimentally validated sChemNET, a deep learning framework to predict small molecules affecting microRNA function based on chemical structure and sequence data ...