Folinic acid, also known as leucovorin, is a medication used to decrease the toxic effects of methotrexate and pyrimethamine. It is also used in combination with 5-fluorouracil to treat colorectal ...

Some people who take methotrexate will need to take folic acid supplements because the medication can diminish the amount of folate in the body. Methotrexate causes the body to waste more of the ...

Methotrexate is a folic acid antagonist. It works by inhibiting the synthesis of purines and pyrimides and therefore interfering with DNA synthesis. Methotrexate affects rapidly dividing cells and ...

Gestational trophoblastic disease (GTD) is a relatively rare but important group of benign and malignant disorders that affect women of child-bearing potential. Most cases are now diagnosed ...

Using lactic acid for skin care can help you have a smoother, brighter complexion. As a gentle alpha hydroxy acid (AHA), lactic acid removes dead skin cells, lightens dark spots, and improves the look ...

1 There were remarkable baseline differences: patients developing AAA had more long-standing, severe disease and less often used concomitant medication including lower doses of methotrexate (MTX), ...