DNA viruses have to deliver their genetic material ... machinery that lacks pathogenic components. Covalent linkage of lipids to drugs could be achieved in several ways depending on the nature ...
SARS-CoV-2 disrupts cholesterol metabolism by using its ORF3a protein to sequester cholesterol in lysosomes, reducing BMP ...
The lipid bilayer contains a mixture of cationic ... DSPC:Chol:PEG–C–DMA:DLin–DMA (20:48:2:30)–siRNA Hepatitis B virus (yes) Mouse model of hepatitis B virus replication [23] DSPC:Chol ...
After viruses infected our evolutionary ancestors, bits of viral DNA lodged themselves into their genomes—and we still carry ...
Viruses are a type of pathogen (germs or tiny microorganism that causes disease) that cause viral infections. Most viral infections, like the common cold, are short-lived and mild. However, there are ...
If you've had more than one friend cancel plans due to a nasty "stomach flu" or "stomach bug," they might actually have ...
Lipids are hydrophobic or amphiphilic small molecules that include sterols, waxes, fatty acids and phospholipids, and are insoluble in water and soluble in organic solvent. Biological lipids are ...
The effect of tenofovir amibufenamide (TMF) on blood lipid profiles in patients with chronic hepatitis B (CHB) remains unclear. This study aimed to explore whether TMF affects blood lipids during ...
These conditions are closely tied to hepatic steatosis, a condition characterized by the abnormal accumulation of fat in the ...
Addressing dyslipidemia is crucial to reducing the burden imposed by cardiovascular disease. However, many current statins have major limitations. Moreover, innovative treatments need to address ...
A high density of tumor-associated macrophages (TAMs) is associated with poorer prognosis and survival in breast cancer patients. Recent studies have shown that lipid accumulation in TAMs can promote ...