On the 7 th day, BMDMs were collected for subsequent experiments. BMDMs were primed with 100 ng/mL ultrapure LPS for 4 h for canonical inflammasome assay. For metabolic assay of NMN, BMDMs were primed ...

In caspase1 dependent pyroptosis, the process is initiated by the assembly of inflammasomes. In caspase-1 non-dependent pyroptosis can be triggered by the interaction between caspase4, caspase5, or ...

McGowan Institute for Regenerative Medicine, Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15219, United States ...

Innate immune cells are white blood cells that mediate innate immunity and include basophils, dendritic cells, eosinophils, Langerhans cells, mast cells, monocytes and macrophages, neutrophils and ...