These include compounds that are active against confirmed bone metastasis targets (OPG, TGF-ß, and colony-stimulating factor), in addition to others that target tumor cells more generally.

Douglas Sacha / Getty Images To get a Social Security card, either for the first time or as a replacement, you have to complete Social Security Form SS-5 and submit at least two supporting ...

Importantly, however, most of the data pointing to the role of autoimmunity in atherosclerosis comes from studies in transgenic mice. Human atherosclerosis is a complex disorder with a complex ...

One critical cytokine that facilitates P-stalk downregulation includes transforming growth factor ß (TGF-ß). As a result, the loss of P-stalk expressing ribosomes inhibits antitumor immune response.

Transforming growth factor-beta (TGF-β), a well-known morphogen, is recognized for its role in regulating growth and development. The study is published in the journal Nature Communications.

Two helmets belonging to World War Two British soldiers massacred by the SS in May 1940 have been discovered and donated to museums in France and England. Only two men survived the execution out ...

8 Beijing Institute of Hepatology, Beijing You’an Hospital, Capital Medical University, Beijing, People's Republic of China Conclusion Our findings underscore the hepatoprotective effect of ECM1, ...

The Laboratory of Tumor Immunology and Immunotherapy, The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat Gan, Israel Introduction: TGFβ is a major immunoinhibitory ...

那么除了Wnt信号之外，是否还会有其他的形态发生素也参与线粒体应激信号的跨组织传递？转化生长因子β（TGF-β）作为一种形态发生素，调控生长发育的功能已广为人知。然而，TGF-β信号能否作为mitokine介导细胞非自主性UPRmt激活，并参与相关生理功能的调控仍 ...

Superstar Mahesh Babu teams up with ace director SS Rajamouli for the highly anticipated action-adventure thriller 'SSMB29'. The film, set to begin shooting in 2025, will feature cutting-edge ...

研究人员通过构建ApoE敲入模型小鼠（简称ApoE-Halo小鼠）发现ApoE主要表达在星形胶质细胞，少量表达在神经元、少突胶质细胞、小胶质细胞上。