In the early phase of Alzheimer’s disease, astrocytes are the primary source of APOE in the brain. This study examined the effects of astrocyte-derived human APOE isoforms in APOE-deficient mouse ...

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HER2 overexpression occurs in approximately 25% of breast cancers and contributes to both tumor growth and metastasis. In a preclinical mouse model of bone metastasis, the monoclonal antibody ...