Thus, neuronal insulin-like signaling appears to be a key regulator of various essential functions in C. elegans, and the metabolic and reproductive defects induced by whole-body deletion of DAF-2 ...

Rutgers Robert Wood Johnson Medical School and collaborating institutions have found that overnutrition leads to insulin ...

A recent study led by Rutgers Robert Wood Johnson Medical School has uncovered a key factor in how overnutrition, or ...

Research from UBC’s Laboratory of Molecular Signalling in Diabetes suggests insulin pathways could be more diverse than ...

nutrient signalling, insulin signalling, stress signalling, morphogen signalling, Hippo signalling, TOR signalling and integrin signalling. In-depth in vivo and in vitro functional analyses ...

One possibility is that in an attempt to overcome the inhibition within the metabolic insulin-signaling pathway, hyperinsulinemia may continue to stimulate the mitogenic insulin-signaling pathway ...

It is also recognized as an important endocrine organ that secretes a number of biologically active signaling proteins ... increase the body’s response to insulin. Studies have also suggested ...

Hypoglycemia is an extremely common side effect of insulin therapy experienced mainly by patients with type 1 diabetes ...

When sufficient energy is available in the body, insulin facilitates the elimination of defective mitochondria. When energy is scarce or when the insulin signal is interrupted, mitochondrial recycling ...

"We know that reducing insulin, and reducing IGF signaling, slows aging and extends lifespan in flies," Tatar said. Tatar approaches the study of aging from the perspective of ecology and ...