Protein function predictions are bioinformatic methods (i.e. involving computation using software) that aim to predict the function of a protein. Protein function analyses use protein sequences ...

To characterize the contributions of individual amino acids to the structure or function of a protein, researchers have adopted directed evolution approaches, which use iterated cycles of ...

In this study, our results uncover the function and mechanism of CHMP5 in the regulation of cell senescence and bone formation in osteogenic cells. Deletion of Chmp5 causes endolysosomal dysfunction ...

TGR5 agonist-induced TER increase as well as JAM-A protein stabilisation was dependent on JAM-A Ser285 phosphorylation. TGR5 agonist-treated mice were protected from cholestasis-induced liver injury, ...

We compute amino acid sequences predicted to fold into proteins with new structures and functions, produce synthetic genes encoding these sequences, and characterize them experimentally. I will ...

Best whey-protein powders Best collagen-protein powder Best plant-based protein powders All the other protein powders I’ve tried Protein powders can be found in thousands of formulations on tens ...

Therefore, we focused on targeting lung cancer caused by the mutant EGFR. Currently, drugs known as tyrosine kinase ...

Department of Physiology, Harold Hamm Diabetes Center, The University of Oklahoma Health Science Center, Oklahoma City, United States ...

Aggregate functions compute a single result from a set of input values. The built-in general-purpose aggregate functions are listed in Table 9.60 while statistical aggregates are in Table 9.61. The ...