A healthy brain balances “activate” and “inhibit” signaling in its neural microcircuitry, with the inhibitory signaling often provided by cell receptors for the neurotransmitter GABA.   Unexpected ...

A healthy brain balances "activate" and "inhibit" signaling in its neural microcircuitry, with the inhibitory signaling often provided by cell ...

Neuroscientist Dr Andrija Sente, who conducted his award-winning research at the Medical Research Council Laboratory of ...

In mice, stress altered the way that the brain packaged memories, resulting in an unnecessary fear response — but drugs were ...

Clobazam exerts it anticonvulsant effects via its selective affinity for the ω 2 site of the GABA-A receptor ... properties of a parent drug and its active or inactive metabolites are greatly ...

According to the above data, the selective agonists of the GABA-A receptor complex are the drugs of first choice in the drug treatment of insomnia. [22] Once treatment has started, monitoring and ...

Net Loss: Net loss attributable to common stockholders for the third quarter of 2024 was $ (3.1) million, or $ (1.92) per share, compared to net income of $0.5 million, or $4.86 per share, for the ...

AbbVie faces setback as schizophrenia trial for emraclidine fails, but still has potential with other assets from Cerevel.

This study presents a valuable finding on the molecular mechanisms that govern GABAergic inhibitory synapse function. The authors propose that Endophilin A1 serves as a novel regulator of GABAergic ...

In today's demanding world, achieving optimal health and maintaining peak performance is more crucial than ever. Many ...

As a recovery guide from the Australian Drug and Alcohol Foundation describes it ... The first is gamma-aminobutyric acid (GABA), a neurotransmitter that slows down your brain by blocking specific ...

AbbVie (ABBV) shares dropped 11% premarket as late-stage trials for schizophrenia drug emraclidine did not meet primary ...